Article
Genetics of sarcoidosis.
Seminars in respiratory and critical care medicine - 1 Jun 2014
Fischer Annegret, Grunewald Johan, Spagnolo Paolo, Nebel Almut, Schreiber Stefan, Müller-Quernheim Joachim
Abstract excerpt
Sarcoidosis is a multifactorial and polygenic disorder. Recently, several novel predisposing genes have been identified by genome-wide association studies, and fast progress in molecular technologies such as systematic and large-scale resequencing will aid the discovery of further risk loci and variants. In this article, the current knowledge of its genetics will be presented, including known and candidate risk...
Topics
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- HLA Antigens
- Humans
- Phenotype
- Sarcoidosis
