Article
Genetics of sarcoidosis.
Clinics in chest medicine - 1 Sept 2008
Müller-Quernheim Joachim, Schürmann Manfred, Hofmann Sylvia, Gaede Karoline I, Fischer Annegret, Prasse Antje, Zissel Gernot, Schreiber Stefan
Abstract excerpt
Sarcoidosis is a multigenic and multifactorial disease. Predisposing genes have been identified and fast progress in molecular technologies including systematic genome-wide association studies and large-scale resequencing will aid the discovery of further risk loci and variants. The exploration of the molecular epidemiology of genetic variants in the pathogenesis of sarcoidosis will allow an assessment of their...
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