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Article

Zip nucleic acids are potent hydrolysis probes for quantitative PCR.

Nucleic acids research - 1 Apr 2010

Paris Clément, Moreau Valérie, Deglane Gaëlle, Voirin Emilie, Erbacher Patrick, Lenne-Samuel Nathalie

Abstract excerpt

Zip nucleic acids (ZNAs) are oligonucleotides conjugated with cationic spermine units that increase affinity for their target. ZNAs were recently shown to enable specific and sensitive reactions when used as primers for polymerase chain reaction (PCR) and reverse-transcription. Here, we report th...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20071749
DOI: 10.1093/nar/gkp1218
PMCID: PMC2853127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20071749-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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