Article
A polymorphism in the CYP17 gene relates to the risk of recurrent pregnancy loss.
Molecular human reproduction - 1 Nov 2003
Sata F, Yamada H, Yamada A, Kato E H, Kataoka S, Saijo Y, Kondo T, Tamaki J, Minakami H, Kishi R
Abstract excerpt
The CYP17 gene encodes the enzyme cytochrome P450c17alpha, which mediates both 17alpha-hydroxylase and 17,20-lyase activity in the steroid biosynthesis pathway. A T-->C polymorphism in the 5' promoter region of CYP17 has been described. To examine the association between recurrent pregnancy loss...
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