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Article

Reduced DNA repair capacity for removing tobacco carcinogen-induced DNA adducts contributes to risk of head and neck cancer but not tumor characteristics.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jan 2010

Wang Li-E, Hu Zhibin, Sturgis Erich M, Spitz Margaret R, Strom Sara S, Amos Christopher I, Guo Zhaozheng, Qiao Yawei, Gillenwater Ann Marie, Myers Jeffrey N, Clayman Gary L, Weber Randal S, El-Naggar Adel K, Mao Li, Lippman Scott M, Hong Waun Ki, Wei Qingyi

Abstract excerpt

PURPOSE: Although cigarette smoking and alcohol use are known risk factors for squamous cell carcinoma of head and neck (SCCHN), only a few exposed individuals develop this disease, suggesting an individual susceptibility. In this study, we investigated the associations between genetically determ...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20068090
DOI: 10.1158/1078-0432.CCR-09-2156
PMCID: PMC2848391

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20068090-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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