Article
Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays.
Genome biology - 12 Jan 2010
Santuari Luca, Pradervand Sylvain, Amiguet-Vercher Amelia-Maria, Thomas Jerôme, Dorcey Eavan, Harshman Keith, Xenarios Ioannis, Juenger Thomas E, Hardtke Christian S
Abstract excerpt
Identification of small polymorphisms from next generation sequencing short read data is relatively easy, but detection of larger deletions is less straightforward. Here, we analyzed four divergent Arabidopsis accessions and found that intersection of absent short read coverage with weak tiling array hybridization signal reliably flags deletions. Interestingly, individual deletions were frequently observed in two...
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