Article
Massive variation of short tandem repeats with functional consequences across strains of Arabidopsis thaliana.
Genome research - 1 Aug 2018
Press Maximilian O, McCoy Rajiv C, Hall Ashley N, Akey Joshua M, Queitsch Christine
Abstract excerpt
Short tandem repeat (STR) mutations may comprise more than half of the mutations in eukaryotic coding DNA, yet STR variation is rarely examined as a contributor to complex traits. We assessed this contribution across a collection of 96 strains of Arabidopsis thaliana, genotyping 2046 STR loci each, using highly parallel STR sequencing with molecular inversion probes. We found that 95% of examined STRs are...
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