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Article

Widely conserved signaling pathways in the establishment of cell polarity.

Cold Spring Harbor perspectives in biology - 1 Aug 2009

McCaffrey Luke Martin, Macara Ian G

Abstract excerpt

How are the asymmetric distributions of proteins, lipids, and RNAs established and maintained in various cell types? Studies from diverse organisms show that Par proteins, GTPases, kinases, and phosphoinositides participate in conserved signaling pathways to establish and maintain cell polarity.

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Identifiers

PMID: 20066082
DOI: 10.1101/cshperspect.a001370
PMCID: PMC2742088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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