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Article

Impact of azithromycin resistance mutations on the virulence and fitness of Chlamydia caviae in guinea pigs.

Antimicrobial agents and chemotherapy - 1 Mar 2010

Binet Rachel, Bowlin Anne K, Maurelli Anthony T, Rank Roger G

Abstract excerpt

Azithromycin (AZM) is a major drug used in the treatment and prophylaxis of infections caused by Chlamydia, yet no significant clinical resistance has been reported for these obligate intracellular bacteria. Nevertheless, spontaneous AZM resistance (Azm(r)) arose in vitro at frequencies ranging f...

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Identifiers

PMID: 20065052
DOI: 10.1128/AAC.01321-09
PMCID: PMC2826001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20065052-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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