Article
Diversity of Chlamydia trachomatis in Trachoma-Hyperendemic Communities Treated With Azithromycin.
American journal of epidemiology - 1 Sept 2018
Chin Stephanie A, Morberg Daniel P, Alemayehu Wondu, Melese Muluken, Lakew Takele, Chen Michael C, Zhou Zhaoxia, Doan Thuy, Cevallos Vicky, Lietman Thomas M, Keenan Jeremy D
Abstract excerpt
Prior studies have theorized that low chlamydial genetic diversity following mass azithromycin treatments for trachoma may create a population bottleneck that prevents the return of infection, but little empirical evidence exists to support this hypothesis. In this study, a single mass azithromycin distribution was administered to 21 communities in the Gurage Zone of Ethiopia in 2003. All children aged 1-5 years...
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