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Article

MMP2 genetic variation is associated with measures of fibrous cap thickness: The Atherosclerosis Risk in Communities Carotid MRI Study.

Atherosclerosis - 1 May 2010

Volcik Kelly A, Campbell Stephen, Chambless Lloyd E, Coresh Josef, Folsom Aaron R, Mosley Thomas H, Ni Hanyu, Wagenknecht Lynne E, Wasserman Bruce A, Boerwinkle Eric

Abstract excerpt

OBJECTIVE: Genetic variation in matrix metalloproteinase (MMP) promoter regions alter the transcriptional activity of MMPs and has been consistently associated with CHD, presumably through plaque degradation and remodeling. We examined the association of MMP promoter variation with multiple plaqu...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20064641
DOI: 10.1016/j.atherosclerosis.2009.12.006
PMCID: PMC2862087

Genes

MMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20064641-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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