Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the platelet GPIIb/IIIa polymorphism with atherosclerotic plaque morphology: the Atherosclerosis Risk in Communities (ARIC) Study.

Atherosclerosis - 1 May 2011

Kucharska-Newton Anna M, Monda Keri L, Campbell Stephen, Bradshaw Patrick T, Wagenknecht Lynne E, Boerwinkle Eric, Wasserman Bruce A, Heiss Gerardo

Abstract excerpt

OBJECTIVES: Platelet activation and aggregation play an important role in the pathogenesis of cardiovascular disease. We examined the association of a single nucleotide polymorphism (SNP) in the GPIIIa platelet glycoprotein (Leu33Pro) with carotid artery plaque morphology and with expression of platelet markers using data from the Atherosclerosis Risk in Communities (ARIC) Carotid MRI study. METHODS: The study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carotid Arteries
Share to Carotid Artery Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Contrast Media

Share to Integrin beta3

Share to P-Selectin

Share to Plaque, Atherosclerotic

Share to Platelet Glycoprotein GPIIb-IIIa Complex

Share to Rupture, Spontaneous

Source

Open in PubMed Open full text

Identifiers

PMID: 21353223
DOI: 10.1016/j.atherosclerosis.2011.01.038
PMCID: PMC3089705

Genes

ITGB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the platelet GPIIb/IIIa polymorphism with atherosclerotic plaque morphology: the Atherosclerosis Risk in Communities (ARIC) Study.PMID 21353223Read ↗

MMP2 genetic variation is associated with measures of fibrous cap thickness: The Atherosclerosis Risk in Communities Carotid MRI Study.Semantic proximity Read ↗

Platelet Pl(A2) allele and incidence of coronary heart disease: results from the Atherosclerosis Risk In Communities (ARIC) Study.Semantic proximity Read ↗

Platelet glycoprotein IIIa Leu33Pro gene polymorphism and coronary artery disease: A meta-analysis of cohort studies.Semantic proximity Read ↗

Carotid ultrasound phenotypes in vulnerable populations.Semantic proximity Read ↗

Sex Differences in Plaque Composition and Morphology Among Symptomatic Patients With Mild-to-Moderate Carotid Artery Stenosis.Semantic proximity Read ↗

Glycoprotein IIIa gene polymorphism and coronary artery disease.Semantic proximity Read ↗

Relationship between glycoprotein IIIa platelet receptor gene polymorphism and coronary artery disease.Semantic proximity Read ↗

Coronary versus carotid artery plaques. Similarities and differences regarding biomarkers morphology and prognosisSemantic proximity Read ↗

Differences between carotid wall morphological phenotypes measured by ultrasound in one, two and three dimensions.Semantic proximity Read ↗

Simultaneous assessment of plaque morphology, cerebral micro-embolic signal status and platelet biomarkers in patients with recently symptomatic and asymptomatic carotid stenosis.Semantic proximity Read ↗

Associations of PPARGC1A haplotypes with plaque score but not with intima-media thickness of carotid arteries in middle-aged subjects.Semantic proximity Read ↗

Mean platelet volume and integrin alleles correlate with levels of integrins α(IIb)β(3) and α(2)β(1) in acute coronary syndrome patients and normal subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.