Article
From primordial germ cell to primordial follicle: mammalian female germ cell development.
Genesis (New York, N.Y. : 2000) - 1 Dec 2006
Pepling Melissa E
Abstract excerpt
In mammals, the final number of oocytes available for reproduction of the next generation is defined at birth. Establishment of this oocyte pool is essential for fertility. Mammalian primordial germ cells form and migrate to the gonad during embryonic development. After arriving at the gonad, the germ cells are called oogonia and develop in clusters of cells called germ line cysts or oocyte nests. Subsequently,...
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