Biosynthesis of human fibroblast growth factor-5.

doi:10.1128/mcb.11.4.1840-1845.1991

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Article

Biosynthesis of human fibroblast growth factor-5.

Molecular and cellular biology - 1 Apr 1991

Bates B, Hardin J, Zhan X, Drickamer K, Goldfarb M

Abstract excerpt

We have analyzed the biosynthesis of human fibroblast growth factor-5 (FGF-5) at the translational and posttranslational levels. FGF-5 RNA synthesized in vitro can be translated in rabbit reticulocyte lysates to yield a 29,500-Da protein, which is consistent with the molecular weight predicted from the coding sequence. The efficiency of FGF-5 translation is dramatically enhanced if an upstream open reading frame...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Line
Cell Transformation, Neoplastic
Fibroblast Growth Factor 5
Fibroblast Growth Factors
Glycosylation
Humans
Immunoblotting
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Molecular Weight

Mutation

Open Reading Frames

Protein Biosynthesis

Rabbits

Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 2005884
DOI: 10.1128/mcb.11.4.1840-1845.1991
PMCID: PMC359856

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2005884-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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