Article
Biosynthesis of human fibroblast growth factor-5.
Molecular and cellular biology - 1 Apr 1991
Bates B, Hardin J, Zhan X, Drickamer K, Goldfarb M
Abstract excerpt
We have analyzed the biosynthesis of human fibroblast growth factor-5 (FGF-5) at the translational and posttranslational levels. FGF-5 RNA synthesized in vitro can be translated in rabbit reticulocyte lysates to yield a 29,500-Da protein, which is consistent with the molecular weight predicted from the coding sequence. The efficiency of FGF-5 translation is dramatically enhanced if an upstream open reading frame...
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