Article
Acquired haemophilia caused by non-haemophilic factor VIII gene variants.
Annals of hematology - 1 Jun 2010
Tiede Andreas, Eisert Roswith, Czwalinna Andreas, Miesbach Wolfgang, Scharrer Inge, Ganser Arnold
Abstract excerpt
The aetiology of anti-factor VIII (FVIII) autoantibody formation in acquired haemophilia remains unknown. We hypothesised that encounter of antigenically different, allogeneic FVIII may challenge inhibitor formation after presentation on MHC class II. Eighteen consecutive cases with acquired haem...
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