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Article

Role of mutation of the circadian clock gene Per2 in cardiovascular circadian rhythms.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Mar 2010

Vukolic Ana, Antic Vladan, Van Vliet Bruce N, Yang Zhihong, Albrecht Urs, Montani Jean-Pierre

Abstract excerpt

Alterations in the circadian blood pressure pattern are frequently observed in hypertension and lead to increased cardiovascular morbidity. However, there are no studies that have investigated a possible implication of the Period2 gene, a key component of the molecular circadian clock, on the circadian rhythms of blood pressure and heart rate. To address this question, we monitored blood pressure, heart rate, and...

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PMID: 20053965
DOI: 10.1152/ajpregu.00404.2009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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