Article

Multi-tissue transcriptome-wide association study identifies genetic mechanisms underlying endometrial cancer susceptibility

2020-12-04

Abstract excerpt

Genome-wide association studies (GWAS) of endometrial cancer have identified 16 genetic susceptibility loci. To identify candidate endometrial cancer susceptibility genes, we have performed the first transcriptome-wide association study (TWAS) of endometrial cancer. For this analysis, we have used the largest endometrial cancer GWAS and gene expression from 48 tissues to maximise statistical power. We used colocal...

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Literature Corpus work: ea1d239e-c6fb-5c3a-8dc6-0a0593974bac
DOI: 10.1101/2020.12.03.20243758

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