Article
Mechanisms of mosaicism, chimerism and uniparental disomy identified by single nucleotide polymorphism array analysis.
Human molecular genetics - 1 Apr 2010
Conlin Laura K, Thiel Brian D, Bonnemann Carsten G, Medne Livija, Ernst Linda M, Zackai Elaine H, Deardorff Matthew A, Krantz Ian D, Hakonarson Hakon, Spinner Nancy B
Abstract excerpt
Mosaic aneuploidy and uniparental disomy (UPD) arise from mitotic or meiotic events. There are differences between these mechanisms in terms of (i) impact on embryonic development; (ii) co-occurrence of mosaic trisomy and UPD and (iii) potential recurrence risks. We used a genome-wide single nucl...
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