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Article

Tigecycline resistance in Serratia marcescens associated with up-regulation of the SdeXY-HasF efflux system also active against ciprofloxacin and cefpirome.

The Journal of antimicrobial chemotherapy - 1 Mar 2010

Hornsey Michael, Ellington Matthew J, Doumith Michel, Hudson Sue, Livermore David M, Woodford Neil

Abstract excerpt

OBJECTIVES: Efflux by RND-type transporters is known to confer resistance to tigecycline in several Enterobacteriaceae species and we examined the potential of this mechanism in Serratia marcescens using a clinical isolate and laboratory-selected mutants. METHODS: Expression of RND-type efflux pu...

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Source

Identifiers

PMID: 20051474
DOI: 10.1093/jac/dkp475

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20051474-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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