Article
Relative roles of heme-irons and globin-thiols in the genesis of acellular hemoglobin mediated vasoconstriction.
Artificial cells, blood substitutes, and immobilization biotechnology - 1 Jan 2010
Kim Hae Won, Hai Chi-Ming, Greenburg A Gerson
Abstract excerpt
In addition to heme-irons, reactive (beta-globin thiols (betaCys93s) of hemoglobin (Hb) also have been shown to interact with endogenous nitric oxide (NO) thereby contributing to vascular tone regulation. What relative roles do these NO binding sites contribute to the overall Hb-mediated vasoacti...
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