Article
Abnormal placental development and early embryonic lethality in EpCAM-null mice.
PloS one - 31 Dec 2009
Nagao Keisuke, Zhu Jianjian, Heneghan Mallorie B, Hanson Jeffrey C, Morasso Maria I, Tessarollo Lino, Mackem Susan, Udey Mark C
Abstract excerpt
BACKGROUND: EpCAM (CD326) is encoded by the tacstd1 gene and expressed by a variety of normal and malignant epithelial cells and some leukocytes. Results of previous in vitro experiments suggested that EpCAM is an intercellular adhesion molecule. EpCAM has been extensively studied as a potential...
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