Article
Autophagy: novel action of panitumumab in colon cancer.
Anticancer research - 1 Dec 2009
Giannopoulou Efstathia, Antonacopoulou Anna, Matsouka Panagiota, Kalofonos Haralabos P
Abstract excerpt
BACKGROUND: Panitumumab, a fully-human monoclonal antibody raised against epidermal growth factor receptor (EGFR), has been approved by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMEA) for the treatment of patients with EGFR-expressing metastatic colorectal carcinoma (mCRC) after failure of standard chemotherapy. Additionally, the guideline of the EMEA includes the use of...
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