Article

The rational modulation of autophagy sensitizes colorectal cancer cells to 5-fluouracil and Oxaliplatin

2023-05-26

Abstract excerpt

<title>Abstract</title><p>Colorectal cancer (CRC) is the third most common and deadliest cancers globally. The primary chemotherapy used for treating CRC is a co-treatment of 5-fluoruracil (5FU) and Oxaliplatin (OXA). In this study, we investigated the cellular mechanisms that contribute to the response and resistance of CRC cells to these drugs using an experimental design mimicking the clinical schedule. To this...

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Literature Corpus work: 32119673-2a63-5c68-be2d-6bf4ed8489ef
DOI: 10.21203/rs.3.rs-2975359/v1

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