Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Berberine regulates the microRNA‑21‑ITGΒ4‑PDCD4 axis and inhibits colon cancer viability

8 Feb 2018

Abstract excerpt

Berberine is sourced from multiple medicinal herb resources and is easy to extract. With the advantages of low price, safety and convenience, berberine may have potential for wide clinical use. The present study aimed to investigate whether berberine inhibited the viability of colon cancer and whether it regulated the three-gene network microRNA (miR)-21-integrin β4 (ITGβ4)-programmed cell death 4 (PDCD4). It was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Berberine and alkaloids research
Share to Cancer-related molecular mechanisms research
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29564000
DOI: 10.3892/ol.2018.7997

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Berberine regulates the microRNA‑21‑ITGΒ4‑PDCD4 axis and inhibits colon cancer viabilityPMID 29564000Read ↗

A Narrative Review on Therapeutic Potential of Naringenin in Colorectal Cancer: Focusing on molecular and biochemical processesSemantic proximity Read ↗

The Mechanism of Aloe-emodin in the Treatment of Colon Cancer based on Network Pharmacological AnalysisSemantic proximity Read ↗

Berberine inhibits tumour growth in vivo and in vitro through suppressing the lincROR-Wnt/β-catenin regulatory axis in colorectal cancerSemantic proximity Read ↗

Berberine sensitizes ovarian cancer cells to cisplatin through miR-21/PDCD4 axis.Semantic proximity Read ↗

Multi-Targeted Anti-Cancer Mechanisms of Li-Ginseng Powder in Colitis-Associated Colorectal Cancer: Integrating Inflammation, Apoptosis and ImmunitySemantic proximity Read ↗

Cancer Pathways Targeted by Berberine: Role of microRNAsSemantic proximity Read ↗

Berberis vulgaris L. Root Extract as a Multi-Target Chemopreventive Agent against Colon Cancer Causing Apoptosis in Human Colon Adenocarcinoma Cell LinesSemantic proximity Read ↗

Nitidine chloride inhibits proliferation and induces apoptosis in colorectal cancer cells by activating the p53 signaling pathwaySemantic proximity Read ↗

Morindone as a potential therapeutic compound targeting TP53 and KRAS mutations in colorectal cancer cells.Semantic proximity Read ↗

Beauvericin Induces Mitochondrial Apoptosis and Attenuates EMT-Associated Phenotypes and Angiogenic Signaling in Colorectal Cancer Cells In Vitro.Semantic proximity Read ↗

Integrative analysis of differential miRNA and functional study of miR-21 by seed-targeting inhibition in multiple myeloma cells in response to berberineSemantic proximity Read ↗

Cincumol prevents malignant phenotype of colorectal cancer cell line HCT116 via inhibiting PI3K/AKT signaling in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.