Article
Spontaneous deleterious mutation in Arabidopsis thaliana.
Proceedings of the National Academy of Sciences of the United States of America - 28 Sept 1999
Schultz S T, Lynch M, Willis J H
Abstract excerpt
The frequency and selective impact of deleterious mutations are fundamental parameters in evolutionary theory, yet they have not been directly measured in a plant species. To estimate these quantities, we allowed spontaneous mutations to accumulate for 10 generations in 1,000 inbred lines of the annual, self-fertilizing plant Arabidopsis thaliana and assayed fitness differences between generations 0 and 10 in a...
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