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Article

Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus.

BMC medical genomics - 31 Dec 2009

Parikh Hemang, Lyssenko Valeriya, Groop Leif C

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) have emerged as a powerful approach for identifying susceptibility loci associated with polygenetic diseases such as type 2 diabetes mellitus (T2DM). However, it is still a daunting task to prioritize single nucleotide polymorphisms (SNPs) from GWAS for further replication in different population. Several recent studies have shown that genetic variation often...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20043853
DOI: 10.1186/1755-8794-2-72
PMCID: PMC2815699

Genes

KCNJ11
NOTCH2
TSPAN8
HHEX
IRS1
KCNQ1
PPARG
WFS1

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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