IL1B rs1143634 polymorphism, cigarette smoking, alcohol use, and lung cancer risk in a Japanese population.

doi:10.1097/JTO.0b013e3181c8cae3

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Article

IL1B rs1143634 polymorphism, cigarette smoking, alcohol use, and lung cancer risk in a Japanese population.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Mar 2010

Kiyohara Chikako, Horiuchi Takahiko, Takayama Koichi, Nakanishi Yoichi

Abstract excerpt

BACKGROUND: Interleukin 1B (IL1B) is involved in pulmonary inflammation induced by environmental or occupational toxins. Chronic inflammation has been implicated in the development of lung cancer. METHODS: We evaluated the role of IL1B (rs1143634, 3954C>T) in a case-control study comprised of 462 lung cancer cases and 379 controls in a Japanese population. Logistic regression was used to assess the adjusted odds...

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PMID: 20035239
DOI: 10.1097/JTO.0b013e3181c8cae3

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