Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Catechol-o-methyltransferase genotype and childhood trauma may interact to impact schizotypal personality traits.

Behavior genetics - 1 May 2010

Savitz Jonathan, van der Merwe Lize, Newman Timothy K, Stein Dan J, Ramesar Raj

Abstract excerpt

We attempt to identify gene by childhood abuse interactions which predispose to the development of schizotypal traits in a familial bipolar disorder (BD) sample. Self-report measures of schizotypal personality traits (Schizotypal Personality Scale) and childhood maltreatment (Childhood Trauma Questionnaire) were administered to 222 participants from 44 families with BD. Variants of catechol-o-methyltransferase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Child Abuse

Share to Environment

Share to Models, Genetic

Share to Schizotypal Personality Disorder

Share to Surveys and Questionnaires

Share to Wounds and Injuries

Source

Identifiers

PMID: 20033274
DOI: 10.1007/s10519-009-9323-7

Genes

COMT
DRD2
DRD4
MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Catechol-o-methyltransferase genotype and childhood trauma may interact to impact schizotypal personality traits.PMID 20033274Read ↗

The relationship between childhood abuse and dissociation. Is it influenced by catechol-O-methyltransferase (COMT) activity?Semantic proximity Read ↗

Catechol-O-methyltransferase (COMT) genotype moderates the effects of childhood trauma on cognition and symptoms in schizophrenia.Semantic proximity Read ↗

COMT but not serotonin-related genes modulates the influence of childhood abuse on anger traits.Semantic proximity Read ↗

Modification of the association between early adversity and obsessive-compulsive disorder by polymorphisms in the MAOA, MAOB and COMT genes.Semantic proximity Read ↗

Interplay between COMT Val158Met, childhood adversities and sex in predicting panic pathology: Findings from a general population sample.Semantic proximity Read ↗

Evaluation of the association COMT Val158Met variant and childhood trauma on aggression in Turkish SCZ patients.Semantic proximity Read ↗

Trauma exposure interacts with the genetic risk of bipolar disorder in alcohol misuse of US soldiers.Semantic proximity Read ↗

Interaction between COMT Val158 Met polymorphism and childhood trauma predicts risk for depression in men.Semantic proximity Read ↗

Interaction between catechol-O-methyltransferase polymorphism and childhood trauma in suicidal ideation of patients with post-traumatic stress disorder.Semantic proximity Read ↗

Stressful life events and catechol-O-methyl-transferase (COMT ) gene in bipolar disorderSemantic proximity Read ↗

Relationship between the COMT-Val158Met and BDNF-Val66Met polymorphisms, childhood trauma and psychotic experiences in an adolescent general population sample.Semantic proximity Read ↗

The interaction of early life experiences with COMT val158met affects anxiety sensitivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.