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Article

Divalent metal-dependent regulation of hepcidin expression by MTF-1.

FEBS letters - 19 Feb 2010

Balesaria Sara, Ramesh Bala, McArdle Harry, Bayele Henry K, Srai Surjit K S

Abstract excerpt

Hepcidin is a small acute phase peptide that regulates iron absorption. It is induced by inflammation and infection, but is repressed by anaemia and hypoxia. Here we further reveal that hepcidin transcription also involves interactions between functional metal response elements (MREs) in its promoter, and the MRE-binding transcription factor-1. Analysis of hepcidin mRNA and protein levels in hepatoma cells...

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Identifiers

PMID: 20026331
DOI: 10.1016/j.febslet.2009.12.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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