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Positive and negative regulators of the metallothionein gene (Review)

9 Mar 2012

Abstract excerpt

Metallothioneins (MTs) are metal-binding proteins involved in diverse processes, including metal homeostasis and detoxification, the oxidative stress response and cell proliferation. Aberrant expression and silencing of these genes are important in a number of diseases. Several positive regulators of MT genes, including metal-responsive element-binding transcription factor (MTF)-1 and upstream stimulatory factor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25760317
DOI: 10.3892/mmr.2015.3459

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