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Article

Modulation of Fgf3 dosage in mouse and men mirrors evolution of mammalian dentition.

Proceedings of the National Academy of Sciences of the United States of America - 29 Dec 2009

Charles Cyril, Lazzari Vincent, Tafforeau Paul, Schimmang Thomas, Tekin Mustafa, Klein Ophir, Viriot Laurent

Abstract excerpt

A central challenge in evolutionary biology is understanding how genetic mutations underlie morphological changes. Because highly calcified enamel enables preservation of detailed dental features, studying tooth morphology enables this question to be addressed in both extinct and extant species. Previous studies have found that mutant mice can have severe abnormalities in tooth morphology, and several authors...

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Identifiers

PMID: 20018768
DOI: 10.1073/pnas.0910086106
PMCID: PMC2799759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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