Article
Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease.
Inflammatory bowel diseases - 1 Aug 2010
Dubinsky Marla C, Mei Ling, Friedman Madison, Dhere Tanvi, Haritunians Talin, Hakonarson Hakon, Kim Cecilia, Glessner Joseph, Targan Stephan R, McGovern Dermot P, Taylor Kent D, Rotter Jerome I
Abstract excerpt
BACKGROUND: Interindividual variation in response to anti-TNFalpha therapy may be explained by genetic variability in disease pathogenesis or mechanism of action. Recent genome-wide association studies (GWAS) in inflammatory bowel disease (IBD) have increased our understanding of the genetic susc...
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