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Article

Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease.

Inflammatory bowel diseases - 1 Aug 2010

Dubinsky Marla C, Mei Ling, Friedman Madison, Dhere Tanvi, Haritunians Talin, Hakonarson Hakon, Kim Cecilia, Glessner Joseph, Targan Stephan R, McGovern Dermot P, Taylor Kent D, Rotter Jerome I

Abstract excerpt

BACKGROUND: Interindividual variation in response to anti-TNFalpha therapy may be explained by genetic variability in disease pathogenesis or mechanism of action. Recent genome-wide association studies (GWAS) in inflammatory bowel disease (IBD) have increased our understanding of the genetic susceptibility to IBD. The aim was to test associations of known IBD susceptibility loci and novel "pharmacogenetic" GWAS...

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Identifiers

PMID: 20014019
DOI: 10.1002/ibd.21174
PMCID: PMC2889173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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