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Article

Colonic Phenotypes Are Associated with Poorer Response to Anti-TNF Therapies in Patients with IBD.

Inflammatory bowel diseases - 1 Aug 2017

Yoon Soon Man, Haritunians Talin, Chhina Sultan, Liu Zhenqiu, Yang Shaohong, Landers Carol, Li Dalin, Ye Byong Duk, Shih David, Vasiliauskas Eric A, Ippoliti Andrew, Rabizadeh Shervin, Targan Stephan R, Melmed Gil Y, McGovern Dermot P B

Abstract excerpt

BACKGROUND: Although anti-tumor necrosis factor (TNF) agents are effective in patients with inflammatory bowel disease (IBD), many patients either do not respond to anti-TNF treatment or lose response over time. The aim of this study was to determine factors associated with response to anti-TNF therapy in IBD. METHODS: Patients with Crohn's disease (CD) or ulcerative colitis who had consented to participate in a...

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Identifiers

PMID: 28590340
DOI: 10.1097/MIB.0000000000001150
PMCID: PMC6510223

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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