Article
Stability of mutant actins.
The Biochemical journal - 15 Feb 1991
Drummond D R, Hennessey E S, Sparrow J C
Abstract excerpt
Mutants of the Drosophila Act88F actin gene were transcribed and translated in vitro and their relative stabilities were examined using urea gradient gel electrophoresis. Most of the mutant actins (E334K, E364K, G366D, G368E and R372H) were as stable as the wild-type. V339I had a slight decrease...
Topics
- Actins
- Animals
- Drosophila
- Drug Stability
- Electrophoresis, Polyacrylamide Gel
- Mutation
- Protein Biosynthesis
- Protein Denaturation
- Rabbits
- Transcription, Genetic
- Urea