Article
Sudden infant death syndrome in mice with an inherited mutation in RyR2.
Circulation. Arrhythmia and electrophysiology - 1 Dec 2009
Mathur Nitin, Sood Subeena, Wang Sufen, van Oort Ralph J, Sarma Satyam, Li Na, Skapura Darlene G, Bayle J Henri, Valderrábano Miguel, Wehrens Xander H T
Abstract excerpt
BACKGROUND: Mutations in the cardiac ryanodine receptor gene (RyR2) have been recently identified in victims of sudden infant death syndrome. The aim of this study was to determine whether a gain-of-function mutation in RyR2 increases the propensity to cardiac arrhythmias and sudden death in youn...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.