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Article

A mechanism for sudden infant death syndrome (SIDS): stress-induced leak via ryanodine receptors.

Heart rhythm - 1 Jun 2007

Tester David J, Dura Miroslav, Carturan Elisa, Reiken Steven, Wronska Anetta, Marks Andrew R, Ackerman Michael J

Abstract excerpt

BACKGROUND: Sudden infant death syndrome (SIDS) is the leading cause of postneonatal mortality in the United States. Mutations in the RyR2-encoded cardiac ryanodine receptor cause the highly lethal catecholaminergic polymorphic ventricular tachycardia (CPVT1) in the young. OBJECTIVE: The purpose of this study was to determine the spectrum and prevalence of RyR2 mutations in a large cohort of SIDS cases. METHODS:...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17556193
DOI: 10.1016/j.hrthm.2007.02.026
PMCID: PMC3332548

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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