Article
Trp64Arg polymorphism of the ADRB3 gene predicts hyperuricemia risk in a population from southern Spain.
The Journal of rheumatology - 1 Feb 2010
Morcillo Sonsoles, Rojo-Martínez Gemma, Martín-Núñez Gracia María, Gómez-Zumaquero Juan Miguel, García-Fuentes Eduardo, Ruiz de Adana Marisol, de la Cruz Almaraz María, Soriguer Federico
Abstract excerpt
OBJECTIVE: To study the role of Trp64Arg polymorphism of the ADRB3 gene in the risk of developing hyperuricemia in 1051 subjects from southern Spain, with a followup of 6 years. The inclusion of plasma levels of uric acid as a diagnostic criterion to define the metabolic syndrome is under discussion. Genes responsible for insulin resistance could contribute to the development of hyperuricemia. Previous...
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