Positive correlation between Beta-3-Adrenergic Receptor (ADRB3) gene and gout in a Chinese male population.

doi:10.3899/jrheum.101037

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Article

Positive correlation between Beta-3-Adrenergic Receptor (ADRB3) gene and gout in a Chinese male population.

The Journal of rheumatology - 1 Apr 2011

Wang Binbin, Meng Dongmei, Wang Jing, Jia Zhaotong, Zhoub Sirui, Liu Shiguo, Chu Nan, Han Lin, Zhang Kun, Ma Xu, Li Changgui

Abstract excerpt

OBJECTIVE: The common polymorphism rs4994 [c. T387C, p. Trp64Arg (W64R)] of the lipolysis regulator beta-3-adrenergic receptor (ADRB3) was identified as a marker in the pathogenesis of hyperuricemia. As gout is characterized by elevated serum concentrations of uric acid, we investigated ADRB3 as a potential candidate for gout. METHODS: This was a prospective case-control study in a group of 421 male patients with...

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PMID: 21285172
DOI: 10.3899/jrheum.101037

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ADRB3

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