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Article

Direct interaction of iron-regulated surface determinant IsdB of Staphylococcus aureus with the GPIIb/IIIa receptor on platelets.

Microbiology (Reading, England) - 1 Mar 2010

Miajlovic Helen, Zapotoczna Marta, Geoghegan Joan A, Kerrigan Steven W, Speziale Pietro, Foster Timothy J

Abstract excerpt

The interaction of bacteria with platelets is implicated in the pathogenesis of endovascular infections, including infective endocarditis, of which Staphylococcus aureus is the leading cause. Several S. aureus surface proteins mediate aggregation of platelets by fibrinogen- or fibronectin-dependent processes, which also requires specific antibodies. In this study S. aureus was grown in iron-limited medium to...

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Source

Identifiers

PMID: 20007649
DOI: 10.1099/mic.0.036673-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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