Article
Involvement of Vts1, a structure-specific RNA-binding protein, in Okazaki fragment processing in yeast.
Nucleic acids research - 1 Mar 2010
Lee Chul-Hwan, Shin Yong-Keol, Phung Thi Thu Huong, Bae Jae Seok, Kang Young-Hoon, Nguyen Tuan Anh, Kim Jeong-Hoon, Kim Do-Hyung, Kang Min-Jung, Bae Sung-Ho, Seo Yeon-Soo
Abstract excerpt
The non-essential VTS1 gene of Saccharomyces cerevisiae is highly conserved in eukaryotes and encodes a sequence- and structure-specific RNA-binding protein. The Vts1 protein has been implicated in post-transcriptional regulation of a specific set of mRNAs that contains its-binding site at their 3'-untranslated region. In this study, we identified VTS1 as a multi-copy suppressor of dna2-K1080E, a lethal mutant...
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