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Article

Gene-gene and gene-environment interactions in HIV-associated nephropathy: A focus on the MYH9 nephropathy susceptibility gene.

Advances in chronic kidney disease - 1 Jan 2010

Núñez Marina, Saran Anita M, Freedman Barry I

Abstract excerpt

HIV-associated nephropathy (HIVAN) is a leading cause of ESRD in African Americans. The HIV-1 virus infects podocytes, cells integral to formation of the glomerular filtration barrier, often leading to focal segmental glomerulosclerosis. HIVAN is typically a complication of late-stage HIV infection, associated with low CD4 cell counts and elevated serum HIV RNA levels. Highly active antiretroviral therapy is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20005488
DOI: 10.1053/j.ackd.2009.08.002
PMCID: PMC2814053

Genes

MYH9

Provenance

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