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Article

The interleukin 6 -174 C/C genotype predicts greater rhinovirus illness.

The Journal of infectious diseases - 15 Jan 2010

Doyle William J, Casselbrant Margaretha L, Li-Korotky Ha-Sheng, Doyle Allison P Cullen, Lo Chia-Yee, Turner Ronald, Cohen Sheldon

Abstract excerpt

BACKGROUND: In adults and children with respiratory syncytial virus (RSV) infection, a polymorphism in the interleukin 6 (IL-6) promoter at position -174 predicts illness magnitude. In addition, polymorphisms in the interleukin 10 (IL-10), tumor necrosis factor alpha (TNF-alpha), and interferon gamma (IFN-gamma) genes are associated with immune responsiveness and the frequency of complications. Here, the effect...

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Identifiers

PMID: 20001857
DOI: 10.1086/649559
PMCID: PMC2943745

Genes

TNF

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Source receipt: pubmed, retrieved 7 Sept 2026.

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