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Telomere shortening and chromosomal instability in myelodysplastic syndromes

8 Dec 2009

Abstract excerpt

Telomere shortening and chromosomal instability are believed to play an important role in the development of myeloid neoplasia. So far, published data are only available on the average telomere length in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML), but not on the telomere length of individual chromosomes. We used a new technique, telomere/centromere-fluorescence in situ hybridization...

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PMID: 19998444
DOI: 10.1002/gcc.20737

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