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Article

Progression in smoldering myeloma is independently determined by the chromosomal abnormalities del(17p), t(4;14), gain 1q, hyperdiploidy, and tumor load.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Dec 2013

Neben Kai, Jauch Anna, Hielscher Thomas, Hillengass Jens, Lehners Nicola, Seckinger Anja, Granzow Martin, Raab Marc S, Ho Anthony D, Goldschmidt Hartmut, Hose Dirk

Abstract excerpt

PURPOSE: The aim of this study was to analyze chromosomal aberrations in terms of frequency and impact on time to progression in patients with smoldering multiple myeloma (SMM) on the background of clinical prognostic factors. PATIENTS AND METHODS: The chromosomal abnormalities 1q21, 5p15/5q35, 9q34, 13q14.3, 15q22, 17p13, t(11;14)(q13;q32), and t(4;14)(p16.3;q32) were assessed in CD138-purified myeloma cells by...

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PMID: 24145347
DOI: 10.1200/JCO.2012.48.4923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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