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Article

Sequencing of HLA-D in responders and nonresponders to short ragweed allergen, Amb a V.

Immunogenetics - 1 Jan 1991

Zwollo P, Ehrlich-Kautzky E, Scharf S J, Ansari A A, Erlich H A, Marsh D G

Abstract excerpt

We investigated the molecular basis for the striking association between HLA-DR2,Dw2 and human immune responsiveness to the Ambrosia artemisiifolia (short ragweed) pollen allergen Amb a V by sequencing the second exons of the DRB and DQB1 genes of 17 selected ragweed-allergic Caucasoid subjects. We also studied the DQA1 allelic polymorphic regions (APRs) in these patients by dot-blotting using sequence-specific...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Cloning, Molecular
Exons
HLA-D Antigens
HLA-DQ Antigens
HLA-DR Antigens
HLA-DR2 Antigen
Humans
Hypersensitivity
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pollen

Polymerase Chain Reaction

Polymorphism, Genetic

Pseudogenes

Source

Identifiers

PMID: 1999353
DOI: 10.1007/BF00210828

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1999353-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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