Article
Epistatic interactions attenuate mutations affecting startle behaviour in Drosophila melanogaster.
Genetics research - 1 Dec 2009
Yamamoto Akihiko, Anholt Robert R H, MacKay Trudy F C
Abstract excerpt
Epistasis is an important feature of the genetic architecture of quantitative traits. Previously, we showed that startle-induced locomotor behaviour of Drosophila melanogaster, a critical survival trait, is highly polygenic and exhibits epistasis. Here, we characterize epistatic interactions among homozygous P-element mutations affecting startle-induced locomotion in the Canton-S isogenic background and in 21...
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