Article
Complex genetic architecture of Drosophila aggressive behavior.
Proceedings of the National Academy of Sciences of the United States of America - 11 Oct 2011
Zwarts Liesbeth, Magwire Michael M, Carbone Mary Anna, Versteven Marijke, Herteleer Liesbet, Anholt Robert R H, Callaerts Patrick, Mackay Trudy F C
Abstract excerpt
Epistasis and pleiotropy feature prominently in the genetic architecture of quantitative traits but are difficult to assess in outbred populations. We performed a diallel cross among coisogenic Drosophila P-element mutations associated with hyperaggressive behavior and showed extensive epistatic and pleiotropic effects on aggression, brain morphology, and genome-wide transcript abundance in head tissues....
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