Article
Low-calorie diet-induced reduction in serum HDL cholesterol is ameliorated in obese women with the -3826 G allele in the uncoupling protein-1 gene.
The Tohoku journal of experimental medicine - 1 Dec 2009
Hamada Taku, Kotani Kazuhiko, Nagai Narumi, Tsuzaki Kokoro, Matsuoka Yukiyo, Sano Yoshiko, Fujibayashi Mami, Kiyohara Natsuki, Tanaka Seitaro, Yoshimura Makiko, Egawa Kahori, Kitagawa Yoshinori, Kiso Yoshinobu, Moritani Toshio, Sakane Naoki
Abstract excerpt
The uncoupling protein-1 (UCP1) gene is of major importance for regulation of body weight and lipid/lipoprotein metabolism. Our cross-sectional study has shown that subjects with the G/G genotype of the -3826 A/G polymorphism in the UCP-1 gene have higher levels of serum high-density lipoprotein...
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