Article

Gene rearrangement in B- and T-lymphoproliferative disease detected by the polymerase chain reaction [see comments]

1991-07-01

Abstract excerpt

Gene rearrangement and monoclonality have been detected in normal cells and in lymphoproliferative disease by using the polymerase chain reaction and primers for the V and J regions of the Ig heavy chain gene or T-cell receptor gamma-chain gene. Using the Ig primers monoclonality was detected in 20 of 20 normal B-lymphocyte clones and in 39 of 52 cases of various types of B-lymphoproliferative disease, but not in...

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Literature Corpus work: c6bc9862-7dd9-5423-97f1-470d7be40370
DOI: 10.1182/blood.v78.1.192.bloodjournal781192

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