Article
Whole-genome single nucleotide polymorphism array analysis is complementary to classical cytogenetic analysis in the evaluation of lymphoid proliferations.
American journal of clinical pathology - 1 Feb 2014
Gibson Sarah E, Luo Jianhua, Sathanoori Malini, Liao Jun, Surti Urvashi, Swerdlow Steven H
Abstract excerpt
OBJECTIVES: To explore how much additional information single nucleotide polymorphism (SNP) arrays provide and whether they could partially replace classical cytogenetics. METHODS: Twenty-six lymphoid proliferations with available cytogenetic studies were analyzed with the Affymetrix Genome-Wide Human SNP Array 6.0 (Affymetrix, Santa Clara, CA). RESULTS: Eleven of 26 cases demonstrated complete concordance...
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